Tuesday, December 6, 2011

Obama fights for Jewish support amid GOP attacks

FILE - In this Dec. 2, 2011 file photo, President Barack Obama speaks at the Interior Department in Washington. Under attack from Republicans portraying him as harsh toward Israel, President Barack Obama is fighting back at public events and in private talks with donors, rabbis and others to shore up his support among Jewish voters, whose backing could be critical in the 2012 election. (AP Photo/Haraz N. Ghanbari, File)

FILE - In this Dec. 2, 2011 file photo, President Barack Obama speaks at the Interior Department in Washington. Under attack from Republicans portraying him as harsh toward Israel, President Barack Obama is fighting back at public events and in private talks with donors, rabbis and others to shore up his support among Jewish voters, whose backing could be critical in the 2012 election. (AP Photo/Haraz N. Ghanbari, File)

(AP) ? President Barack Obama and his Republican opponents are clashing over U.S. policy toward Israel as each side jockeys for support from Jewish voters, who could be critical in the 2012 election.

Aiming to cast Obama as unfairly harsh toward Israel and soft on the Palestinians, Republican presidential hopefuls Mitt Romney and Newt Gingrich have called on the president to fire his ambassador to Belgium. The envoy, Howard Gutman, had said that some anti-Semitism stemmed from tensions between Israel and the Palestinians; Romney and Gingrich say his remarks unfairly blamed Israel.

The White House says Obama has a strong record on support for Israel, and quickly fired back with a statement condemning "anti-Semitism in all its forms." The State Department said Gutman would remain in his job.

Republicans also challenged Obama's assertion at a fundraiser last week that "this administration has done more in terms of the security of the state of Israel than any previous administration." Romney said Obama has "repeatedly thrown Israel under the bus" ? an accusation the Republican National Committee repeated Monday.

Firing back, Democratic National Committee Chairwoman Debbie Wasserman Schultz called Romney's comments "outrageous" and questioned his own policies. The White House cited military aid to Israel and support at the United Nations, and pointed to statements from Israeli officials backing up Obama's assertion.

The fiery debate will likely continue Wednesday when the GOP presidential candidates attend a Washington forum hosted by the Republican Jewish Coalition.

Obama campaign officials say they will be ready to respond. And the next day, Jewish leaders will be at the White House for briefings on Israel and a Hanukkah party, followed by an Obama speech next week to an expected audience of nearly 6,000 at a conference of the Union for Reform Judaism.

Such attention is all being paid in recognition that Jewish voters, though comprising only 2 percent of the electorate nationwide, are an important part of Obama's base and could make the difference in battleground states including Florida, Pennsylvania, Ohio and Nevada in a close election. Moreover, the Jewish community is an important source of donations, and Obama campaign supporters want to maintain that support as much as Republicans want to chip away at it.

"This campaign takes the Jewish vote very, very seriously," said Ira Forman, the Obama campaign Jewish outreach director. "I'm confident this will be the most comprehensive effort in presidential campaign history."

The White House outreach has increased since May when Obama caused a furor by calling for Israel's 1967 borders, with agreed-upon land swaps, as a basis for resuming negotiations toward a two-state solution with the Palestinians. Israeli Prime Minister Benjamin Netanyahu rejected the '67 borders as indefensible and largely disregarded Obama's emphasis on land swaps to account for current conditions.

Republicans seized on the dispute. And while Obama supporters say his argument was widely mischaracterized, damage was done. Now the Obama campaign and its backers say they are determined to respond rapidly to such criticism in future.

"We are trying to responsibly respond to all of these unsubstantiated or false allegations, but there are so many of them, and they are so frequently recited despite the fact that the people who are spreading them have to know that they're false, that it's hard to keep up with them," said Alan Solow, an Obama fundraiser and longtime associate.

The effort involves using surrogates including Vice President Joe Biden, and use of the president's own time in public appearances and private talks with donors and religious leaders, such as a conference call between Obama and rabbis ahead of the Jewish New Year this fall.

The Obama campaign also is going on the offense against Republicans. In conversations about the Jewish vote, Obama backers are quick to bring up comments by Romney, Gingrich and Rick Perry at a debate last month suggesting they would start foreign aid for all countries at zero. Obama supporters say would imperil funding for Israel, even though the candidates also sought to affirm their support for the Jewish state.

Democratic candidates typically enjoy a big electoral advantage among Jewish voters. Obama won 78 percent of the Jewish vote in 2008, compared with 21 percent for Republican John McCain.

But Gallup has found that Obama's approval rating among Jews has fallen from 83 percent in January 2009 to 54 percent in late summer and early fall of this year. Still, that figure is much higher than his overall 41 percent approval rating, and the drop-off in support was about in line with other voter groups.

Sid Dinerstein, chairman of the Palm Beach County Republican Party in Florida, predicted that Obama would be limited to around 60 percent of the Jewish vote in 2012. Obama backers say that won't happen, but it could mean a potentially decisive difference of tens of thousands of votes in key states.

A candidate's position on Israel may not be the top issue for most Jewish voters, who like others are more motivated by jobs and the economy. But it's important to many, and Republicans see an opening, given the consternation over Obama's 1967 borders speech, his administration's rebukes of Israel for building settlements in disputed areas, and a recent incident in which Obama was overheard appearing to endorse criticism of Netanyahu from French President Nicolas Sarkozy.

"The reality is that the Jewish community understands that on a number of critical issues this administration has undermined not only the U.S.-Israel relationship, but has made Israel more vulnerable," said Matt Brooks, executive director of the Republican Jewish Coalition.

Brooks points to the recent upset in New York's special election to replace Democratic Rep. Anthony Weiner, in which Republican Bob Turner won in the heavily Jewish district. Brooks says this was a warning sign to Obama on his stance on Israel. Obama supporters say other factors were at play, including the heavily Orthodox and more conservative makeup of the district.

But even strong supporters are disappointed that Obama has not yet traveled to Israel in his capacity as president, after delivering a major speech in Cairo early in his administration. An Israel trip had been rumored to be in the works but seems unlikely to happen prior to the 2012 election.

Democratic Rep. Steve Rothman said he remains hopeful a trip will happen in the next year.

"No president has been perfect on every subject, though history will record that Obama has been the best president for Israel when it comes to military and intelligence support," said Rothman of New Jersey.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2011-12-05-US-Obama-Jewish-Voters/id-f0cb9ea562f244f78142cc8db6237881

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You can lead a penguin to water, but can you make him swim?

When it comes to water, penguins aren't naturals.

"Some of them are terrified," says Bethany Wlaz, a keeper at the Maryland Zoo in Baltimore.

So each time African penguins are born into the zoo's breeding program for the endangered birds, someone like Wlaz becomes their swimming coach. But first comes the introduction to being wet.

Soft as a cotton ball and about the size of a roasted chicken, Male One ? hatched on Oct. 12 ? is lowered into a stainless steel sink by Wlaz and Betty Dipple, another animal keeper.

"Araaah," the bird protests, as a stream of lukewarm water washes over its head and flippers. "Araaah."

Back and belly, tail feathers and webbed feet, nothing escapes the faucet. Five minutes later, the penguin's first bath is in the can.

While Male One is being dried and wrapped in a fluffy towel, Male Two ? four days younger ? gets the same treatment and emits a similar donkey-like bray. Puffs of gray down float in the air.

"They're getting the full salon service," Wlaz says.

Doting on African penguins has been a Maryland Zoo specialty for more than three decades. With 55 to 65 birds living at the moat-enclosed area known as Rock Island, the zoo has one of the largest breeding colonies in the country. Another major colony is at the New England Aquarium in Boston.

The work is of global importance because African penguins, found only along the southern shore and islands of Africa, are teetering on the edge of extinction. Their numbers have declined from as many as 4 million in the early 1900s to 60,000 in 2010, according to the Southern African Foundation for the Conservation of Coastal Birds. Fewer than half of them are estimated to be breeding pairs.

African penguin eggs were targeted up until the 1960s by people who considered them a delicacy and scooped them up by the millions. The penguins' habitat has been destroyed by commerce and oil spills, and overfishing and climate change have depleted their food, according to the International Union for Conservation of Nature and Natural Resources.

The Assn. of Zoos and Aquariums has developed a species survival plan to map out breeding to ensure a strong genetic pool while scientists and conservation groups try to stabilize the population. The Maryland Zoo keeps breeding pairs on hand and distributes other penguins to zoos for display or breeding.

The parents of Male One and Male Two ? proper names are coming, zoo officials promise ? came to Baltimore a year ago. The father hailed from Tampa and the mother from Memphis. They quickly became a family of four, with the newborns spending three weeks with their parents before keepers took over the domestic duties.

"It's hard to have an entirely bad day when you're around penguins," Dipple says as she slides a chunk of squid into the gaping black beak of Male One.

The chicks weigh 4.9 pounds and 3.8 pounds. When fully grown right around Christmas, they'll be 23 to 25 inches tall, will weigh about 8 pounds and will be fully decked out in black-and-white plumage.

Once Male One and Male Two get the hang of being wet, the keepers will fill a small pool halfway with water and shoo the birds in. This march of the penguins will happen three times a day, every day, until the lessons take.

"For each bird, it will click at a different point," Wlaz said. "Some we'll put in and they'll take to it. Some will run and jump out like it's molten lava. One day they realize that it's the coolest thing in the world and they start diving and swimming, and then it's pretty much impossible to get them out."

Soon, they may have siblings. The parents have produced another clutch, and four other penguin pairs are expected to breed this season.

That's a lot of swimming lessons.

candy.thomson@baltsun.com

Source: http://feeds.latimes.com/~r/latimes/news/science/~3/JYL5NeNZF5k/la-na-penguin-chicks-20111204,0,4883065.story

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Monday, December 5, 2011

Yahoo shuts down The Projector and The Set blogs (Reuters)

LOS ANGELES (TheWrap.com) ? Yahoo is letting The Projector and The Set flicker out and die, the movie and television blogs acknowledged on Twitter Friday.

"As was just announced, Yahoo has decided to let @YahooProjector shuffle off this mortal coil. It's a damn shame: We were having such fun," Will Leitch, the site's co-editor, tweeted.

The Set tweeted similar news. Both sites said that a number of blogs will be closing as well.

It was not immediately clear what other blogs will join the two fansites in the blogosphere in the sky.

The Projector is a co-production between Leitch and Tim Grierson. The Set is run by Lindsay Robertson and Tara Ariano.

Both sites features reviews, news items and film clips, written with a fun and semi-autobiographical flare. The two sets of editors are friends, according to the sites.

"We're obviously quite sad about this: We were having so much fun, something we sometimes fear is lacking in movie writing," The Projector editors tweeted on the site's Twitter feed.

They said they would be busy screen-grabbing old reviews, so they don't disappear along with the site.

Source: http://us.rd.yahoo.com/dailynews/rss/internet/*http%3A//news.yahoo.com/s/nm/20111202/media_nm/us_yahoo

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Sunday, December 4, 2011

Not all cellular reprogramming is created equal

Thursday, December 1, 2011

Tweaking the levels of factors used during the reprogramming of adult cells into induced pluriopotent stem (iPS) cells greatly affects the quality of the resulting iPS cells, according to Whitehead Institute researchers.

"This conclusion is something that I think is very surprising or unexpected?that the levels of these reprogramming factors determine the quality of the iPS cells," says Whitehead Founding Member Rudolf Jaenisch. "We never thought they'd make a difference, but they do."

An article describing this work is published in the December 2 issue of Cell Stem Cell.

iPS cells are made by introducing specific reprogramming genes into adult cells. These factors push the cells into a pluripotent state similar to that of embryonic stem (ES) cells. Like ES cells, iPS cells can become any cell type in the body, a characteristic that could make them well-suited for therapeutic cell transplantation or for creating cell lines to study such diseases as Parkinson's and Alzheimer's.

Since the creation of the first iPS cells in 2006, researchers using various reprogramming techniques have reported a broad spectrum of efficiency rates and quality of resulting iPS cells. Although researchers have shown iPS cells can fulfill all developmental tests applied to ES cells, recent reports have identified molecular differences that can influence their developmental potential and render them less-than-equivalent partners to ES cells. These inconsistencies have tarnished the promise of iPS cells, dampened enthusiasm, and fueled speculation that they may never be used therapeutically.

In one example reported last year, a lab created iPS cells using a cutting-edge technique in which a piece of DNA containing four reprogramming genes is safely integrated in the genome of adult mouse cells. In this highly publicized study, the resulting iPS cells performed poorly in tests of pluripotency and failed to produce adult mice, which is the most stringent test of pluripotency. Yet again this called into question the fidelity by which reprogramming factors could consistently generate fully reprogrammed cells equivalent to ES cells. Many in the field saw this as another nail in the coffin of iPS cells.

To Bryce Carey, first author of the Cell Stem Cell paper and a graduate student in Jaenisch's lab at the time, this death knell seemed premature. He repeated the experiment, changing a few details, including the order in which the reprogramming factors were placed on the inserted piece of DNA. Surprisingly, such small alterations had a profound effect?more adult cells were converted to high-quality iPS cells than in the earlier, nearly identical study.

"We are trying to show that the reprogramming process is not as flawed as some have thought, and that you can isolate these fully pluripotent iPS cells that have all of the developmental potential as embryonic stem cells at a pretty high frequency," says Carey, who is now a postdoctoral associate at Rockefeller University. "A lot of times these parameters are very difficult to control, so while the approach first described by [Shinya] Yamanaka back in 2006 is still the most reliable method for research purposes, we should be cautious in concluding there are inherent limitations. We show recovery of high-quality cells doesn't have to be the exception."

###

Whitehead Institute for Biomedical Research: http://www.wi.mit.edu/index.html

Thanks to Whitehead Institute for Biomedical Research for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/115654/Not_all_cellular_reprogramming_is_created_equal

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Saturday, December 3, 2011

Children with HIV/AIDS falling through the cracks of treatment scale-up efforts

ScienceDaily (Dec. 1, 2011) ? Less than one-quarter (23%) of children with HIV/AIDS who need treatment are getting it, according to a report released by the World Health Organization (WHO) on the occasion of World AIDS Day (1 December 2011). Although treatment coverage for adults has been steadily climbing and has now reached approximately half of those in need, coverage for children is lagging far behind, highlighted the Drugs for Neglected Diseases initiative (DNDi), a non-profit research and development organization that has recently launched a new paediatric HIV drug development programme.

'Children with HIV/AIDS are falling through the cracks', said Dr Bernard P?coul, Executive Director of the DNDi. '250,000 children died of HIV-related complications in 2010 -- that's nearly 700 each day. This is simply unacceptable.'

There are several reasons for this situation -- including lack of access for pregnant women to antenatal care, HIV testing, and antiretrovirals (ARVs) to prevent mother-to-child transmission and treat expecting mothers, as well as difficulties diagnosing HIV in infants. But one of the most important, and overlooked, is the lack of suitable formulations of ARVs adapted for children, particularly babies and toddlers. The reason for this neglect lies, ironically, with the success of the virtual elimination of HIV among newborns in wealthy countries.

'There's little profit to be made from developing treatments for the millions of children with HIV/AIDS, 90% of whom are the poorest of the poor in sub-Saharan Africa, and the lack of market incentive means pharmaceutical companies do not develop ARVs adapted to their needs', Dr P?coul continued. 'Without treatment, half of the children born with HIV die before their second birthday.'

WHO recommends immediate ART for all HIV-positive children less than two years old, but the safety and correct dosing have not been established in very young children for the majority of ARVs approved for adults. In addition, key existing paediatric ARV formulations taste bad, require impractical multiple liquid preparations and refrigeration, and have undesirable interactions with tuberculosis (TB) drugs.

DNDi's new paediatric HIV programme aims to develop an improved first-line therapy for children under three years of age. Ideally, this ARV combination therapy needs to be easy to administer and better tolerated by children than current drugs, as well as heat stable and easily dispersible (dissolvable in water or breast milk). It must also carry minimal risk for developing resistance and require minimum weight adjustments. Finally, any new formulations must be compatible with TB drugs.

'Given the current funding crisis, we are deeply concerned that children with HIV/AIDS -- who are already invisible and largely voiceless -- will fall even further down on the agenda', said Dr Marc Lallemant, Head of DNDi's Paediatric HIV Programme. 'And while everything possible needs to be done to achieve the long-term goal of "eliminating" new infections among infants, including through scale-up of prevention of mother-to-child transmission programmes, a more serious response is urgently needed for HIV-positive children today.'

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Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/kxyzj5BhUsg/111201105405.htm

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Monday, November 28, 2011

Moroccans hold Arab Spring-inspired election

Moroccans voted for a new parliament Friday in Arab Spring-inspired elections that are facing a boycott by democracy campaigners who say the ruling monarchy isn't committed to real change.

A moderate Islamist party and a pro-palace coalition led by the finance minister are competing for the top spot, but a key test for the authorities' legitimacy will be how many voters cast ballots.

The king amended the constitution over the summer giving the prime minister new powers, including the ability to dissolve parliament and make certain appointments, in response to pro-democracy protests. But the ultimate authority remains with the king.

The election result will be closely watched by Morocco's U.S. and other Western allies, as well as European tourists who cherish its beaches and resorts, to see how this North African kingdom navigates its own Arab Spring.

In the affluent Agdal neighborhood of Rabat, a steady stream of professionals lined up early in the morning at a polling station to vote before work.

"I've always voted, but this time it is more important," said Dr. Mohammed Ennabli. "Before it was the king who chose, now it is the people who choose."

Many people, however, scorned a process they say has been going on for decades without any tangible effect on their lives.

"I won't vote, the promises are never kept ? with or without the new constitution, it is the same," said Abdallah Cherachaoui, an unemployed 45 year old in the lower income district of Akkari. "They are laughing at us."

In the working class city of Sale, across the river from the capital Rabat, there was a steady trickle of voters to the school acting as a polling station, but some stayed outside.

"I voted in 2007 because the candidate was a member of my family, but he also disappointed me and as soon as the elections were over, I never saw him again, so I'm not making that mistake again," said Brahim Errami, 25, from his seat in a nearby cafe. "I pity the people going in and out of that school."

Morocco's reputation as a stable kingdom in North Africa has taken a hit with this year's protests over government corruption and heavy handed security forces. And its once-steady economy is creaking from the amount of money the government has pumped into raising salaries and subsidies to keep people calm amid the Arab world turmoil.

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The election campaign has been strangely subdued, unlike the lively politicking in nearby Tunisia when it held the first elections prompted by the Arab uprisings last month.

Morocco with its many political parties and regular elections under the tight control of an all-powerful monarch was once the bright star in a region of dictatorships.

But all that has changed with the Arab uprisings that toppled dictators in Tunisia, Libya and Egypt. Now a political system that holds elections but leaves all powers in the hands of a hereditary king does not look so liberal.

Some 31 political parties are fielding 5,392 candidates to compete for 395 seats in parliament, including 60 set aside for women and 30 for "youth," under 40.

A complex proportional system of representation means no party is likely to take more than 20 percent of the seats.

Under the new constitution, the king asks the party with the most seats to form the government, which could well be the Islamist Justice and Development party, known by its French initials PJD. But there's uncertainty over whether it can truly change anything in the face of the palace's power.

The Islamists' biggest rival for the top spot is Finance Minister Salaheddine Mezouar's Rally of Independents, which leads an alliance of seven other pro-palace parties.

"This is a very important election for the Moroccan people and it confirms the choice made for an open process of democratization that is being consolidated by this election," he told The Associated Press after voting. "This is really a moment of great emotion."

Like elsewhere in the Arab world, Moroccans hit the streets in the first half of 2011 calling for more democracy, and King Mohammed VI responded by amending the constitution and bringing forward elections.

But since then the sense of change has dissipated, and while the king remains a respected figure, few have much confidence in parliament or the politicians in it.

"I voted because we need to elect a new parliament, but I voted blank for the simple reason that there is no one I can trust from the people that are being elected," said Chamseddin Baba, the manager of an IT company who voted in the wealthy suburb of Souissi. "I would like to vote for the best, but the best are not there."

The 2007 elections, the first with widespread international observation, had just 37 percent turnout, and some fear it could be even lower this time around.

Now, however, the number of registered voters has dropped from 15 million to 13.5 million, despite population increases, so turnout will almost certainly be higher.

There will be 3,200 election observers, though they will likely only cover a fraction of the 40,000 polling stations scattered across the country.

Copyright 2011 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://www.msnbc.msn.com/id/45432955/ns/world_news-africa/

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